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With a proven track record in regenerative medicene, you're in safe hands
Chronic obstructive pulmonary disease (COPD) is a term used to describe a group of lung conditions that cause difficulty in breathing. Symptoms also may include a persistent chesty cough, often accompanied by phlegm, and frequent chest infections. The two most common forms of COPD are emphysema and bronchitis. COPD is usually progressive, hence it is likely to worsen if left untreated and may lead to significant lung damage.
COPD is usually diagnosed in patients aged in their 50s or older and is linked to factors such as smoking, exposure to fumes or dust, or genetic predisposition. Treatments include lifestyle changes, inhalers and drugs that make it easier to breathe, or in some cases surgery or lung transplant. Research suggests stem cell therapy may also be an option for certain patients with COPD.
Stem cell treatment is a relatively new discipline of regenerative medicine. Where there is an established medical need, a clinician may now prescribe stem cell therapy as a treatment within the UK, in accordance with regulation by the Human Tissue Authority.
Please Note: Whilst the clinic does offer stem cell treatments, no treatment is undertaken until the patient has been reviewed by a consultant (who is a specialist in the relevant field) and approval has been given by the specialist. Patients are informed throughout the process of the limitations of stem cell treatment and it is for the patient to make a final decision in conjunction with his or her consultant.
“Regenerative treatments are an option for people who may have already tried, or considered, conventional treatments. Research using stem cells with latest technology has shown promising results.”
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“Stem cells are located throughout the body and act as natural healers. Studies suggest that when used for medical purposes, stem cells have the potential to accelerate tissue repair, stimulate tissue regeneration, and decrease inflammation.”
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contact us by clicking here
Stem cells are known to possess unique biological properties, including the ability to self-renew. They can also change into different types of cell in order to perform specific functions with the body's healing process and immune system. They can also issue instructions to other types of regenerative cells. These properties make stem cells of interest in the field of COPD research, which has resulted in a number of studies and clinical trials.
A study published in 2017 stated: "Stem cell based therapy offers a promising therapeutic approach that has shown potential in diverse degenerative lung diseases. Preclinical studies have demonstrated encouraging outcomes of mesenchymal stem/stromal cells (MSCs) therapy for lung disorders including emphysema, bronchopulmonary dysplasia, fibrosis, and acute respiratory distress syndrome."
It is estimated that that 3 million people in the UK alone have COPD, of whom 2 million remain undiagnosed. If the condition is spotted relatively early, it is often possible to slow any further decline in lung function through conventional treatment. Hence, improving a patient's quality of life and enabling them to remain active. However, for many people COPD can continue to have a dramatic impact on their everyday life.
Many patients with COPD have both emphysema and bronchitis. Emphysema damages the small air sacs known as alveoli, which exist within the lungs. This reduces the amount of oxygen that can reach the bloodstream. Emphysema also reduces the surface area of the lungs and causes them to lose their elasticity, leading to shortness of breath, especially when exercising.
Bronchitis occurs when the airways of the respiratory system, known as the bronchi, become irritated and inflamed. It can be a temporary problem caused by an infection or a chronic condition that reoccurs and worsens over time. People with bronchitis may experience a hacking cough and the bringing up of mucus, along with wheezing and tightness of the chest.
WHAT ARE STEM CELLS?
Stem cells are special types of cell that occur naturally within the body. They have the ability to replicate themselves or develop into different types of cells through a process known as differentiation.
Hence stem cells have the potential to become new cells in order to perform specific functions. For example, they can differentiate to become blood cells or other types of cell that are active within the immune system. This process enables stem cells not only to play a unique role in the body's ability to heal itself, but also to encourage the growth of healthy tissue.
HOW ARE STEM CELLS USED IN MEDICINE?
Whist stem cell therapy is relatively new, stem cells have been the subject of over 40 years of research and there have been a large number of clinical trails. A limited number of treatments for certain medical conditions are now available in the UK.
When used for medical purposes, research suggests stem cells can accelerate tissue repair, stimulate tissue regeneration, decrease inflammation, and stimulate new blood vessel growth.
WHAT TREATMENTS ARE THERE FOR COPD?
There are number of established treatments for COPD, which your doctor can advise you upon. These include inhalers that contain steroids and / or bronchodilators such as salbutamol in order to reduce inflammation. Patients may also be offered special exercise programmes and lifestyle advice, such as giving up smoking.
In severe cases, surgery may be recommended or even lung transplants for a small number of patients. However, recent advances in medical research suggest that stem therapy may also have potential to play a role in the treatment of COPD.
In particular, mesenchymal stem cells (MSCs) have the ability to regulate inflammation and boost tissue regeneration. Hence, research suggests that MSC therapy holds promise for the treatment of chronic lung diseases, especially when administered at an early stage.
CAN I HAVE STEM CELL THERAPY?
Stem cell therapy may be considered for people who require an alternative approach to established procedures. It may be suitable for patients aged 18 to 75 or children in special circumstances, whose condition is stable enough to undergo treatment.
The first stage is to book a consultation with a qualified medical practitioner, who will assess your medical history in order to potentially make a pre-approval application. A multi-disciplinary panel of experts will then consider your application.
If you application is approved, you will then be invited undergo a full health screening and detailed tests to ensure stem cell treatment is an appropriate approach for you. Provided you pass the assessment criteria, you may then begin treatment.
WHAT DOES TREATMENT INVOLVE?
Patients generally require a preparation period that may involve a number of procedures to ensure your regenerative system is at its most receptive. The stem cells can typically then be injected into the body, which depending on the nature of your condition can either be done intravenously or by intra-tissue injection; or a combination of both.
WHERE DO THE STEM CELLS COME FROM?
The stem cells may be either 'autologous' or 'allogeneic' and are contained in a prescription created by a regulated medical supplier. Autologous stem cells are processed after being harvested from tissue within the patient's own body, whereas allogeneic stem cells are cultured in a laboratory from a donated source. The prescription is then transferred into the patient.
HOW ARE STEM CELLS REGULATED?
Stem cell therapies are classed as nouvelle treatments or 'specials', which are a permissible category of medicines that are available to meet the clinical needs of an individual patient.
We work with LifePlus Stem Cells, who are regulated to sell and market pure stem cells products as an unlicensed medicine in accordance with quality and safety standards under its own HTA and MHRA licences (The Human Tissue Act 2004 and associated regulation/The Human Tissue (Quality and Safety for Human Application) Regulations 2007 (as amended).
The progress of stem cell patients is carefully monitored and we have a regulatory duty to report any relevant findings to the Royal Free Hospital in London, with a view to stem cell therapy becoming a standardised licensed treatment.
The Cellular & Regenerative practice in Harley Street was co-founded by Dr Aamer Khan, author of the forthcoming book, 'Aesthetic Treatments in Regenerative Medicine: Stem Cells, Stromal Vascular Fraction, Platelet Rich Plasma, and Platelet Rich Fibrin.'
Qualifying as a doctor at the University of Birmingham in 1986 with an MB ChB (Bachelor of Medicine, Bachelor of Surgery), Dr Khan completed his postgraduate training in University Hospitals Birmingham. He spent 24 years working within the NHS, including many years in General Practice. In 2010, he retired from the NHS to refine protocols at the Harley Street Skin Clinic.
Dr Mike Tees MB, BChir, BSc (Hons), DLO, DRCOG, MRCGP, is a Cambridge medical grad and has racked up over 25 years of experience in the medical profession. Dr Tee is well regarded as an expert in Dermal Fillers, PRP, Thread Lifts, Mole Removal & dermatological minor surgery.
1 - Mesenchymal Stem Cell Administration in Patients with Chronic Obstructive Pulmonary Disease: State of the Science - STEM CELLS INTERNATIONAL
2 - The potential of mesenchymal stem cell therapy for chronic lung disease
NHS: COPD Overview
Healthline: About COPD
LifePlus Stem Cells: Clinical Evidence & Research Papers
LifePlus Stem Cells: FAGs from Doctors and Patients
Follow two of our celebrity patients on their journey to becoming their better selves
Every step of your journey with Harley Street Skin is handled with the utmost care and diligence. From your very first consultation, right the way through to follow up and aftercare, Harley Street Skin will guide, advise and support you at every given opportunity. We want to make sure that your time with us is as special to you, as you are to us...
The answer to some of the most common questions you may have
It's only natural to have questions if you are considering pursuing a treatment for the first time, and at Harley Street Skin, it's important to us that you feel confident and comfortable at every stage of your journey. To help you find the answers you need, here are a few of the more common quibbles that we find our clients frequently ask...
OPD is usually caused by long-term factors that trigger inflammation in the lungs.
This can take the form of exposure to tobacco smoke, airborne dust, chemicals, vapours, air pollution, and genetic or environmental factors. Some, however may unfortunately go on to develop COPD as a result of their genetic predisposition.
Stem cells excrete messenger cells called cytokines to promote healing and regeneration in damaged lung tissue.
It then sends messages to the local repair system and directs regeneration to the afflicted areas of the lungs and airways. At the same time, stem cells work to reduce inflammation in the airways by suppressing the immune response. Stem cell treatment is the closest you will get to a lung transplant due to its ability to regrow damaged tissue.
Stem cell treatment alleviates symptoms such as breathlessness and chronic coughing, and reduces long-term risk of fatigue and weight loss. Inflammation of the airways will be eased by stem cells and counter the effect of narrowing which should improve your quality of life and ability to exercise.
This is evident in the potential for stem cells to counteract an overactivation of the immune system which is what leads to acute inflammation of the airways. Clinical trials show patients can exhale more air after a deep breath than they could before stem cell treatment for COPD.
Mesenchymal stem cells are delivered intravenously before they travel to the lungs and begin to work on the immune system to combat the inflammation and repair damage to alveoli structures. It does this automatically and stops stimulating the growth of tissue once repair is complete.
Aside from surgery or a lung transplant, the only other available methods of COPD treatment are solely focused on slowing the progression of COPD.
Stem cell treatment, on the other hand, can uniquely regenerate damaged tissue and reduce inflammation in the airways making it a much more effective long-term treatment than any other procedure aimed at relieving symptoms of COPD.
While inhalers can ease the narrowed airways temporarily, stem cells provide a long-lasting form of treatment with long-term benefits.
The award winning clinic dedicated to helping you be your best self
We understand that deciding to go forward with cosmetic treatment can feel like a huge decision. One that we certainly wouldn't expect you to go ahead with without hearing a little bit about us first. Here is exactly why people around the world are happy to put their trust into Harley Street Skin Clinic.
Since 2004, Harley Street Skin has been on speed dial to some of the world's highest flyers thanks to the expertise of cosmetic tour de force, Dr. Aamer Khan and wife Lesley Reynolds.
With their flagship clinic based on the world’s most famous medical strip, Harley Street Skin quickly became a medical and cosmetic frontrunner, drumming up a pristine professional reputation and impressive roster of celebrity clientele. The clinic was in fact so thriving that it gained the attention of television network SkyOne, becoming the focus of hit documentary series Stitch Me, Lift Me, Tuck Me.
Offering an expansive range of both surgical and non-surgical treatments, Harley Street Skin are renowned worldwide for their cosmetic precision, expertise and minimally invasive techniques. From top of the line body sculpting treatments and cosmetic contouring to breast enhancement and discreet anti-ageing lifts, Harley Street experts offer the A-list experience from consultation through to aftercare.
But that's not all. Harley Street Skin are also pioneering skincare specialists, offering solutions to everything from anti-ageing and resurfacing, to colour correction and hydration.
Carefully formulating the perfect regime for even the most stubborn and unusual of skin complaints, Harley Street Skin boast an acclaimed skin care range frequently making an appearance in beauty mag must-haves, health and lifestyle columns, and celebrity handbags around the world.
With highly skilled practitioners, doctors and surgeons on hand at every turn, Harley Street Skin can help you attain the aesthetic you've been dreaming of - whatever your cosmetology needs.