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With a proven track record in regenerative medicene, you're in safe hands
Diabetes is a metabolic condition that causes a person's blood sugar levels to fluctuate irregularly. It affects over 400 million people around the world, including 5 million people in the UK alone. Diabetes occurs when the body cannot make enough insulin, or can’t effectively utilise insulin in order to regulate glucose levels in the blood.
There are two main types of diabetes, Type 1 or Type 2, both of which when left untreated can result in damage to the nerves, eyes, kidneys and other major organs, including risk of heart attack. Thankfully, there are a number of treatments available. These include insulin injections or drugs such as metformin, which can help to lower blood sugar.
Research suggests that stem cell therapies may also be able to play a positive role in the future treatment of diabetes. Stem cell treatment is a relatively new discipline of regenerative medicine. Where there is an established medical need, a clinician may now prescribe stem cell therapy as a treatment within the UK, in accordance with regulation by the Human Tissue Authority.
Please Note: Whilst the clinic does offer stem cell treatments, no treatment is undertaken until the patient has been reviewed by a consultant (who is a specialist in the relevant field) and approval has been given by the specialist. Patients are informed throughout the process of the limitations of stem cell treatment and it is for the patient to make a final decision in conjunction with his or her consultant.
“Regenerative treatments are an option for people who may have already tried, or considered, conventional treatments. Research using stem cells with latest technology has shown promising results.”
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“Stem cells are located throughout the body and act as natural healers. Studies suggest that when used for medical purposes, stem cells have the potential to accelerate tissue repair, stimulate tissue regeneration, and decrease inflammation.”
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contact us by clicking here
When the body functions healthily, glucose in bloodstream can be stored in cells until it is needed for energy. However, people with diabetes are unable to process carbohydrates in the normal manner. Hence those affected by diabetes often spend their lives managing symptoms and carefully calculating their dietary requirements around the clock.
However, research in a number of countries, including in the UK and USA, suggests that stem cells may be able to play a role in treating Type 1 and Type 2 diabetes. For example, a study published in 2014 stated: "The recent progress in regenerative medicine, especially stem cell therapy, has suggested several novel and potential cures for T1D (Type 1 diabetes)."
When we are healthy, the body is able to process normal levels of glucose, which flows through the blood vessels. However, when the body is unable make use of insulin these levels increase and can result in a state called hyperglycemia.
Symptoms of hyperglycemia include excessive thirst, increased urination (particularly at night), blurred vision, and fatigue. Conversely, some medications for diabetes can cause low blood sugar, which is known as hypoglycemia. This can lead to sweating, tiredness, dizziness and trembling.
Diabetes occurs when insulin-producing beta cells are either destroyed by the immune system or do not function properly. There are a number of clinical trials underway to evaluate how stem cells may be beneficial for diabetes. Research includes looking at ways to produce fully working beta cells from stem cells.
WHAT ARE STEM CELLS?
Stem cells are special types of cell that occur naturally within the body. They have the ability to replicate themselves or develop into different types of cells through a process known as differentiation.
Hence stem cells have the potential to become new cells in order to perform specific functions. For example, they can differentiate to become blood cells or other types of cell that are active within the immune system. This process enables stem cells not only to play a unique role in the body's ability to heal itself, but also to encourage the growth of healthy tissue.
HOW ARE STEM CELLS USED IN MEDICINE?
Whist stem cell therapy is relatively new, stem cells have been the subject of over 40 years of research and there have been a large number of clinical trails. A limited number of treatments for certain medical conditions are now available in the UK.
When used for medical purposes, research suggests stem cells can accelerate tissue repair, stimulate tissue regeneration, decrease inflammation, and stimulate new blood vessel growth.
WHAT TREATMENTS ARE THERE FOR DIABETES?
There are a number of treatments to treat diabetes, which your doctor can advise you upon. Hence many people with diabetes are able to lead a good quality of life.
Type 1 diabetes can be treated via insulin injections or pumps. Type 2 diabetes (which is the most common type) can be managed through healthy lifestyle choices (such as diet and exercise) and / or by using insulin or other medications.
However, research into the use of stem cells has also shown promising results for treating diabetes and further studies are underway. Where there is an established medical need, it may be possible for certain diabetes patients to explore cellular options.
CAN I HAVE STEM CELL THERAPY?
Stem cell therapy may be considered for people who require an alternative approach to established procedures. It may be suitable for patients aged 18 to 75 or children in special circumstances, whose condition is stable enough to undergo treatment.
The first stage is to book a consultation with a qualified medical practitioner, who will assess your medical history in order to potentially make a pre-approval application. A multi-disciplinary panel of experts will then consider your application.
If you application is approved, you will then be invited undergo a full health screening and detailed tests to ensure stem cell treatment is an appropriate approach for you. Provided you pass the assessment criteria, you may then begin treatment.
WHAT DOES TREATMENT INVOLVE?
Patients generally require a preparation period that may involve a number of procedures to ensure your regenerative system is at its most receptive. The stem cells can typically then be injected into the body, which depending on the nature of your condition can either be done intravenously or by intra-tissue injection; or a combination of both.
WHERE DO THE STEM CELLS COME FROM?
The stem cells may be either 'autologous' or 'allogeneic' and are contained in a prescription created by a regulated medical supplier. Autologous stem cells are processed after being harvested from tissue within the patient's own body, whereas allogeneic stem cells are cultured in a laboratory from a donated source. The prescription is then transferred into the patient.
HOW ARE STEM CELLS REGULATED?
Stem cell therapies are classed as nouvelle treatments or 'specials', which are a permissible category of medicines that are available to meet the clinical needs of an individual patient.
We work with LifePlus Stem Cells, who are regulated to sell and market pure stem cells products as an unlicensed medicine in accordance with quality and safety standards under its own HTA and MHRA licences (The Human Tissue Act 2004 and associated regulation/The Human Tissue (Quality and Safety for Human Application) Regulations 2007 (as amended).
The progress of stem cell patients is carefully monitored and we have a regulatory duty to report any relevant findings to the Royal Free Hospital in London, with a view to stem cell therapy becoming a standardised licensed treatment.
The Cellular & Regenerative practice in Harley Street was co-founded by Dr Aamer Khan, author of the forthcoming book, 'Aesthetic Treatments in Regenerative Medicine: Stem Cells, Stromal Vascular Fraction, Platelet Rich Plasma, and Platelet Rich Fibrin.'
Qualifying as a doctor at the University of Birmingham in 1986 with an MB ChB (Bachelor of Medicine, Bachelor of Surgery), Dr Khan completed his postgraduate training in University Hospitals Birmingham. He spent 24 years working within the NHS, including many years in General Practice. In 2010, he retired from the NHS to refine protocols at the Harley Street Skin Clinic.
Dr Mike Tees MB, BChir, BSc (Hons), DLO, DRCOG, MRCGP, is a Cambridge medical grad and has racked up over 25 years of experience in the medical profession. Dr Tee is well regarded as an expert in Dermal Fillers, PRP, Thread Lifts, Mole Removal & dermatological minor surgery.
1 - Mesenchymal stem cell-based therapy for type 1 diabetes
2 - Mesenchymal stem cell therapy in Type 2 diabetes mellitus
3 - Diabetes UK: Stem cells into beta cells
Healthline: Everything you need to know about diabetes
LifePlus Stem Cells: FAGs from Doctors and Patients
Follow two of our celebrity patients on their journey to becoming their better selves
Every step of your journey with Harley Street Skin is handled with the utmost care and diligence. From your very first consultation, right the way through to follow up and aftercare, Harley Street Skin will guide, advise and support you at every given opportunity. We want to make sure that your time with us is as special to you, as you are to us...
The answer to some of the most common questions you may have
It's only natural to have questions if you are considering pursuing a treatment for the first time, and at Harley Street Skin, it's important to us that you feel confident and comfortable at every stage of your journey. To help you find the answers you need, here are a few of the more common quibbles that we find our clients frequently ask...
At its most basic, it is a cell replacement therapy. Stem cells are highly intuitive and have the ability to grow/develop into various forms of cell and function accordingly. The base objective in diabetic care is to use adult or embryonic tissue to generate new pancreatic b-cells which replace those that have failed, been damaged or destroyed.
These stem cells are first harvested (from either fat, bone marrow or umbilical lining) of a donor, propagated in a laboratory, and finally reinjected into the patient.
From a scientific standpoint, treatment using MSCs (multipotent mesenchymal stem cells) has been seen to reduce hyperglycemia in type 2 sufferers by significantly stimulating beta-cell regeneration. This is acheived by increased vascularization of the pancreatic islets, as well as the general improvement of the endocrine system.
Whilst, at present, you could not claim that stem cell treatment offers a comprehensive cure, there certainly has been lots of reported success in symptom alleviation.
Stem Cells are harvested from a nominated donor, and can be found in either adipose cells (fat), bone marrow, or umbilical lining (as is the case with embryonic stem cells.
Whilst some people feel more comfortable making use of their own adult stem cells for treatment, others may pursue embryonic stem cells for their significantly-higher concentration. They are harvested very soon after birth in a GMP-regulated laboratory, and are always thoroughly screened for infection, genetic abnormality and disease in the lab prior to use.
Patients needn't worry about experiencing any pain whilst donating or receving stem cells for treatment, as local anaesthetic is always used to ensure the patient is most comfortable throughout.
At present, stem cells are being trialled to circumvent the need for human intervention when it comes to insulin requirements. A small study which was then convered by The Daily Telegraph duped stem cell transplants as a surefire 'cure' for type 1 diabetes, with many participants not needing their usual daily injections for up 2 and a half years after the trial.
Whilst it is still too early to comment on what this might mean for type 1 sufferers longterm, recent studies have already seen significant boosts in beta-cell function when using stem cells, with patients also requiring decreased insulin dosage, and seeing accelerated wound healing from diabetic foot ulcers.
There has even been some evidence to suggest that, in the case of early diagnosis, it may even be able to help bolster and almost 'reset' the body's immune system so that it stops attacking the pancreas, and fend off the onset of symptoms.
For now, however, stem cell treatment is predominantly focused on the variety of diabetes that it can aid: Type 2.
Stem cell treatment has had much reported success when it comes to type 2 diabetes, and treatment itself will help alleviate many side effects of the condition.
In addition to unstable blood sugar levels, those who are continually impacted by a lack of energy, increased thirst, fatigue, unexplained weight fluctuation, blurred vision, frequent urination, slow healing, unpredictable appetite and even repeated infections will, in particular, find treatment to be lifechanging.
Most importantly, however, Stem cell treatment serves as a very effective means of fighting back against further degredation. Type 2 diabetes is a progressive condition, which may eventually cause complete b-cell function shutdown. This means that the cells may no longer produce enough additional insulin to overcome the insulin resistance. Through the use of regenerative stem cell treatment, we are able to help support and rebuild the necessary functions to prevent diabetes from reaching the point of no return.
You may experience some slight tenderness and/or bruising following stem cell treatment, although symptoms should settle within just a few days of treatment.
Whilst there is no formal 'recovery period', we do recommend that patients do not travel by airplane for a minimum of 5 days.
The award winning clinic dedicated to helping you be your best self
We understand that deciding to go forward with cosmetic treatment can feel like a huge decision. One that we certainly wouldn't expect you to go ahead with without hearing a little bit about us first. Here is exactly why people around the world are happy to put their trust into Harley Street Skin Clinic.
Since 2004, Harley Street Skin has been on speed dial to some of the world's highest flyers thanks to the expertise of cosmetic tour de force, Dr. Aamer Khan and wife Lesley Reynolds.
With their flagship clinic based on the world’s most famous medical strip, Harley Street Skin quickly became a medical and cosmetic frontrunner, drumming up a pristine professional reputation and impressive roster of celebrity clientele. The clinic was in fact so thriving that it gained the attention of television network SkyOne, becoming the focus of hit documentary series Stitch Me, Lift Me, Tuck Me.
Offering an expansive range of both surgical and non-surgical treatments, Harley Street Skin are renowned worldwide for their cosmetic precision, expertise and minimally invasive techniques. From top of the line body sculpting treatments and cosmetic contouring to breast enhancement and discreet anti-ageing lifts, Harley Street experts offer the A-list experience from consultation through to aftercare.
But that's not all. Harley Street Skin are also pioneering skincare specialists, offering solutions to everything from anti-ageing and resurfacing, to colour correction and hydration.
Carefully formulating the perfect regime for even the most stubborn and unusual of skin complaints, Harley Street Skin boast an acclaimed skin care range frequently making an appearance in beauty mag must-haves, health and lifestyle columns, and celebrity handbags around the world.
With highly skilled practitioners, doctors and surgeons on hand at every turn, Harley Street Skin can help you attain the aesthetic you've been dreaming of - whatever your cosmetology needs.