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With a proven track record in regenerative medicene, you're in safe hands
Parkinson's disease is a debilitating neurodegenerative disorder that leads to a lack of control over the body. It is caused by a loss of nerve cells in the brain, which results in a reduction in dopamine levels. Since dopamine is a vital chemical messenger that connects the brain to the central nervous system, people with Parkinson's disease may experience problems with movement, involuntary shaking, and cognitive difficulty.
Treatments for Parkinson's include medication or surgery to control the various physical and mental health issues that are associated with the condition. Supportive treatments such as physiotherapy and speech therapy can be helpful. Research suggests that stem cell therapy may also have the potential to benefit patients with Parkinson's disease.
Stem cell treatment is a relatively new discipline of regenerative medicine. Where there is an established medical need, a clinician may now prescribe stem cell therapy as a treatment within the UK, in accordance with regulation by the Human Tissue Authority.
Please Note: Whilst the clinic does offer stem cell treatments, no treatment is undertaken until the patient has been reviewed by a consultant (who is a specialist in the relevant field) and approval has been given by the specialist. Patients are informed throughout the process of the limitations of stem cell treatment and it is for the patient to make a final decision in conjunction with his or her consultant.
“Regenerative treatments are an option for people who may have already tried, or considered, conventional treatments. Research using stem cells with latest technology has shown promising results.”
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“Stem cells are located throughout the body and act as natural healers. Studies suggest that when used for medical purposes, stem cells have the potential to accelerate tissue repair, stimulate tissue regeneration, and decrease inflammation.”
If you wish to learn more please
contact us by clicking here
Parkinson's disease is thought to affect 145,000 people in the UK alone, equivalent to around one in every 350 of the adult population. It is usually appears between the ages of 50 and 60, and affects both men and woman, although it is more common in men. The underlying causes of Parkinson's are unknown, although it may be linked to lifestyle and genetic factors.
Stem cell research is of interest in relation to Parkinson's disease because stem cells have the ability to repair or regenerate damaged tissue, including nerve cells within the brain. According to Parkinson's UK, which provides help and support for people with the condition, "Stem cell therapy has the potential to lead to new and better treatments for Parkinson's disease."
The severity of Parkinson's can be divided into five stages, with stage 1 being very mild and stage 5 being the most advanced. People with stage 1 may experience few symptoms, if any, whereas people with stage 5 are likely to require around the clock assistance and may experience dementia and hallucinations.
Symptoms appear when dopamine-producing nerve cells die off in a part of the brain called the substantia nigra. Medications for Parkinson's include levodopa, which helps to replenish dopamine. However, stem cells are of interest because they have the potential to develop into any kind of cell in the body, including dopamine-producing neurons.
A study published in 2018 stated: "Recent advances in the field of cellular reprogramming and personalized medicine now allow for previously unattainable cell therapies and patient-specific modelling of PD (Parkinson's disease) using induced pluripotent stem cells." Further studies and trials are now underway.
WHAT ARE STEM CELLS?
Stem cells are special types of cell that occur naturally within the body. They have the ability to replicate themselves or develop into different types of cells through a process known as differentiation.
Hence stem cells have the potential to become new cells in order to perform specific functions. For example, they can differentiate to become blood cells or other types of cell that are active within the immune system. This process enables stem cells not only to play a unique role in the body's ability to heal itself, but also to encourage the growth of healthy tissue.
HOW ARE STEM CELLS USED IN MEDICINE?
Whist stem cell therapy is relatively new, stem cells have been the subject of over 40 years of research and there have been a large number of clinical trails. A limited number of treatments for certain medical conditions are now available in the UK.
When used for medical purposes, research suggests stem cells can accelerate tissue repair, stimulate tissue regeneration, decrease inflammation, and stimulate new blood vessel growth.
WHAT TREATMENTS ARE THERE FOR PARKINSON'S DISEASE?
There are number of treatments for the symptoms of Parkinson's disease, which your doctor can advise upon. These include medications that help to replenish dopamine or act by imitating its action within the brain.
Patients may also benefit from adequate rest, exercise, and a balanced diet, along with supportive measures such as speech therapy and physical therapy. In some cases, brain surgery may be recommended.
Studies into the use of stem cells for treating Parkinson's disease have shown promising results and a clinical trails are now underway in several different countries.
CAN I HAVE STEM CELL THERAPY?
Stem cell therapy may be considered for people who require an alternative approach to established procedures. It may be suitable for patients aged 18 to 75 or children in special circumstances, whose condition is stable enough to undergo treatment.
The first stage is to book a consultation with a qualified medical practitioner, who will assess your medical history in order to potentially make a pre-approval application. A multi-disciplinary panel of experts will then consider your application.
If you application is approved, you will then be invited undergo a full health screening and detailed tests to ensure stem cell treatment is an appropriate approach for you. Provided you pass the assessment criteria, you may then begin treatment.
WHAT DOES TREATMENT INVOLVE?
Patients generally require a preparation period that may involve a number of procedures to ensure your regenerative system is at its most receptive. The stem cells can typically then be injected into the body, which depending on the nature of your condition can either be done intravenously or by intra-tissue injection; or a combination of both.
WHERE DO THE STEM CELLS COME FROM?
The stem cells may be either 'autologous' or 'allogeneic' and are contained in a prescription created by a regulated medical supplier. Autologous stem cells are processed after being harvested from tissue within the patient's own body, whereas allogeneic stem cells are cultured in a laboratory from a donated source. The prescription is then transferred into the patient.
HOW ARE STEM CELLS REGULATED?
Stem cell therapies are classed as nouvelle treatments or 'specials', which are a permissible category of medicines that are available to meet the clinical needs of an individual patient.
We work with LifePlus Stem Cells, who are regulated to sell and market pure stem cells products as an unlicensed medicine in accordance with quality and safety standards under its own HTA and MHRA licences (The Human Tissue Act 2004 and associated regulation/The Human Tissue (Quality and Safety for Human Application) Regulations 2007 (as amended).
The progress of stem cell patients is carefully monitored and we have a regulatory duty to report any relevant findings to the Royal Free Hospital in London, with a view to stem cell therapy becoming a standardised licensed treatment.
The Cellular & Regenerative practice in Harley Street was co-founded by Dr Aamer Khan, author of the forthcoming book, 'Aesthetic Treatments in Regenerative Medicine: Stem Cells, Stromal Vascular Fraction, Platelet Rich Plasma, and Platelet Rich Fibrin.'
Qualifying as a doctor at the University of Birmingham in 1986 with an MB ChB (Bachelor of Medicine, Bachelor of Surgery), Dr Khan completed his postgraduate training in University Hospitals Birmingham. He spent 24 years working within the NHS, including many years in General Practice. In 2010, he retired from the NHS to refine protocols at the Harley Street Skin Clinic.
Dr Mike Tees MB, BChir, BSc (Hons), DLO, DRCOG, MRCGP, is a Cambridge medical grad and has racked up over 25 years of experience in the medical profession. Dr Tee is well regarded as an expert in Dermal Fillers, PRP, Thread Lifts, Mole Removal & dermatological minor surgery.
1 - Treatment of Parkinson’s Disease through Personalized Medicine and Induced Pluripotent Stem Cells
NHS: Parkinson's disease
Healthline: Parkinson's disease Overview
LifePlus Stem Cells: Clinical Evidence & Research Papers
LifePlus Stem Cells: FAGs from Doctors and Patients
Follow two of our celebrity patients on their journey to becoming their better selves
Every step of your journey with Harley Street Skin is handled with the utmost care and diligence. From your very first consultation, right the way through to follow up and aftercare, Harley Street Skin will guide, advise and support you at every given opportunity. We want to make sure that your time with us is as special to you, as you are to us...
The answer to some of the most common questions you may have
It's only natural to have questions if you are considering pursuing a treatment for the first time, and at Harley Street Skin, it's important to us that you feel confident and comfortable at every stage of your journey. To help you find the answers you need, here are a few of the more common quibbles that we find our clients frequently ask...
Parkinson's Disease is a result of nerve damage in the brain, and is sustained from a loss of dopamine in the body. Dopamine is a neurohormone which is secreted into the blood, and plays the role of a neurotransmitter, helping send signals to other nerve cells - of which your brain has nearly 100 billion of.
Dopamine is produced in several different areas of the brain, including the substantia nigra, the hypothalamus and the ventral tegmental area. When the body is no longer able to produce the necessary amount of dopamine, it has difficulty communicating messages to the parts of the brain which plan and control movement. Dopamine dysfunction is also linked to certain symptoms of depression, which is why many PD patients often wrestle with low mood simultaneously, and why those that suffer with depression also experience lethargy and lack of motivation.
Exactly why people go on to develop Parkinsons is still, sadly, unknown. However, thanks to scientific development, we are on the brink of being able to prevent it's further development.
The worsening of apparent PD symptoms is the result of steadily decreasing levels of dopamine. This means that, over time, degeneration on a cellular level is what is what is responsibile for the physiological decay that we see before us.
When we are able to identify and locate this cellular decay, replenishing it with healthy, functioning cells, we can do a great deal to improve both the inside and outside aftermath of nerve damage. This is exactly the logic behind stem cell treatment.
Stem cells can both migrate to different areas of the body and perform the necessary roles of the cells they are replacing. Stem cell therapy for Parkinson's Disease travels to the nerce cells responsible for dopamine-production - the 'Dopaminergic neurons' - and begin reparations, restoring function to the body as a result.
In short, stem cell treatment for Parkinson's Disease will introduce new dopamine cells to the body. By doing this, we are able to replace what is lost in PD and see a drastic reduction in both physical and mental symptoms that are associated with it.
PD sufferers that seek out stem cell treatment experience replenishment on a cellular level.
This can lead to improvement in such things as:
|Difficulties with Speech|
|Rigidity and Pain|
Stem cells used to treat Parkinson's Disease target production of what is known as 'dopaminergic neurons' in order to combat dopamine deficiency. Stem cells with the ability to do so can be sourced from various different areas around the human body, and are either sourced from the patient themselves (as is the case with 'autologous' treatment) or from a donor (known as 'allogeneic' treatment).
These cells can be found in bone marrow, fat and in umbilical tissue. Treatment using umbilical tissue - referred to as embryonic stem cell treatment - is often favoured over treatment using adult stem cells due to a dramatic increase in potency.
The award winning clinic dedicated to helping you be your best self
We understand that deciding to go forward with cosmetic treatment can feel like a huge decision. One that we certainly wouldn't expect you to go ahead with without hearing a little bit about us first. Here is exactly why people around the world are happy to put their trust into Harley Street Skin Clinic.
Since 2004, Harley Street Skin has been on speed dial to some of the world's highest flyers thanks to the expertise of cosmetic tour de force, Dr. Aamer Khan and wife Lesley Reynolds.
With their flagship clinic based on the world’s most famous medical strip, Harley Street Skin quickly became a medical and cosmetic frontrunner, drumming up a pristine professional reputation and impressive roster of celebrity clientele. The clinic was in fact so thriving that it gained the attention of television network SkyOne, becoming the focus of hit documentary series Stitch Me, Lift Me, Tuck Me.
Offering an expansive range of both surgical and non-surgical treatments, Harley Street Skin are renowned worldwide for their cosmetic precision, expertise and minimally invasive techniques. From top of the line body sculpting treatments and cosmetic contouring to breast enhancement and discreet anti-ageing lifts, Harley Street experts offer the A-list experience from consultation through to aftercare.
But that's not all. Harley Street Skin are also pioneering skincare specialists, offering solutions to everything from anti-ageing and resurfacing, to colour correction and hydration.
Carefully formulating the perfect regime for even the most stubborn and unusual of skin complaints, Harley Street Skin boast an acclaimed skin care range frequently making an appearance in beauty mag must-haves, health and lifestyle columns, and celebrity handbags around the world.
With highly skilled practitioners, doctors and surgeons on hand at every turn, Harley Street Skin can help you attain the aesthetic you've been dreaming of - whatever your cosmetology needs.