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Stem Cell Treatment for Parkinson's Disease In London

With over half a million procedures undertaken, you're in safe hands

Parkinson's Disease is a debilitating neurodegenerative disorder. For sufferers, this means experiencing an increasing loss of control over their bodies - a prospect that is understandably both frightening and anxiety-inducing.

For many, Parkinson's Disease was something that, once diagnosed, would inevitably progress to a point where motor skills ground almost to a halt. Patients felt trapped by a disorder which may - at first - be characterised by mild tremors, but would eventually progress to the point of incapacitating palsy.

That was until stem cell research posed hope to hundreds of thousands of sufferers worldwide. Decades worth of in-depth, biological research finally culminating in a potential method of disease reversal. Finally, a treatment plan focused less on merely the management of the disease's symptoms, and more on the repair of the underlying malfunction itself.

Lesley Says

“Stem cells have the potential to develop into every kind of cell about the human body which makes treatment amazingly versatile. Any conditions characterised by inflammation can see tangible benefits.”

Dr Khan Says

“We can effectively restore the biological structures that have damaged by a degenerative condition using stem cells. For those with Parkinsons, for example; treatment can mean a new lease of life.”

Stem Cell Treatment For Parkinsons Info

The remarkable difference a Harley Street Skin Clinic treatment can provide

Stem cell treatment for Parkinson's Diseases is possible due to it's ability to prompt dopamine-producing nerve cells - the type of brain cells affected in Parkinson's Disease - in certain neurons that are associated with motor skills.

Studies making use of autologous mesenchymal cells found in the bone marrow ['autologous' meaning sourced from the same individual] showed a marked improvement on the recognised Parkinson's severity scale known as the 'Unified Parkinson's Disease Rating Scale' (UPDPS). This UPDPS score is determined through a 50 question assessment, looking at both motor and non-motor symptoms. This testing revealed that, after treatment, patients saw an astonishing reduction in symptoms and subsequently had improved posture as well as better muscle control; speech and general mobility.

Previously, the only methods of controlling PD symptoms that were available to patients were physiotherapy, precarious surgeries and the use of certain drug therapies which were indisputably linked to all sorts of side effects, both physiological and psychological. Thanks to advances in the understanding of how transplanted stem cells may replace and repair the damaged nerve cells responsible for movement, degeneration to the point of paralysis is now no longer an inevitability. It is an end-stage symptom which may potentially be prevented.

Stem Cell Treatment for Parkinsons

Parkinson's Disease is caused by a loss of nerve cells in a specific part of the brain - nerve cells in this area are responsible for making what we call dopamine - a 'feel-good' hormone and chemical messenger that connects the brain to the nervous system. When the nerve cells that produce dopamine are damaged, and our dopamine levels decrease, we can no longer effectively communicate with the part of the brain responsible for movement, and PD symptoms become apparent.

Stem Cell Treatment for Parkinsons

Symptoms are progressive, and consist of both motor and cognative function issues. This may include: difficulties with speech, muscle spasms, impaired balance or flexibility, bradykinesia (slowed movement), anosmia (loss of smell), insomnia, memory problems, anxiety and depression. There are 5 recognised stages of Parkinson's Disease, ranging from 1: mild tremors sometimes apparent on just one side of the body, to 5: severe difficulty walking/standing and, in some cases, hallucination.

Stem Cell Treatment for Parkinsons

Prior to stem cell therapy, PD treatment was concerned mostly with the management of symptoms, yet did very little for the objective improvement of the condition. These options included: analgesics, neuro-steroids, hydro/physiotherapy, 'Deep Brain Stimulation' surgery - or sometimes a complex combination thereof. Thankfully now, doctors are able to target the origins of PD on a biological level using stem cells, and patients can regain control over a condition which previously allowed them very little.

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Stem Cell Treatment for Parkinsons FAQs

The answer to some of the most common questions you may have

It's only natural to have questions if you are considering pursuing a treatment for the first time, and at Harley Street Skin, it's important to us that you feel confident and comfortable at every stage of your journey. To help you find the answers you need, here are a few of the more common quibbles that we find our clients frequently ask...

Parkinson's Disease is a result of nerve damage in the brain, and is sustained from a loss of dopamine in the body. Dopamine is a neurohormone which is secreted into the blood, and plays the role of a neurotransmitter, helping send signals to other nerve cells - of which your brain has nearly 100 billion of.

Dopamine is produced in several different areas of the brain, including the substantia nigra, the hypothalamus and the ventral tegmental area. When the body is no longer able to produce the necessary amount of dopamine, it has difficulty communicating messages to the parts of the brain which plan and control movement. Dopamine dysfunction is also linked to certain symptoms of depression, which is why many PD patients often wrestle with low mood simultaneously, and why those that suffer with depression also experience lethargy and lack of motivation.

Exactly why people go on to develop Parkinsons is still, sadly, unknown. However, thanks to scientific development, we are on the brink of being able to prevent it's further development.

The worsening of apparent PD symptoms is the result of steadily decreasing levels of dopamine. This means that, over time, degeneration on a cellular level is what is what is responsibile for the physiological decay that we see before us.

When we are able to identify and locate this cellular decay, replenishing it with healthy, functioning cells, we can do a great deal to improve both the inside and outside aftermath of nerve damage. This is exactly the logic behind stem cell treatment.

Stem cells can both migrate to different areas of the body and perform the necessary roles of the cells they are replacing. Stem cell therapy for Parkinson's Disease travels to the nerce cells responsible for dopamine-production - the 'Dopaminergic neurons' - and begin reparations, restoring function to the body as a result.

In short, stem cell treatment for Parkinson's Disease will introduce new dopamine cells to the body. By doing this, we are able to replace what is lost in PD and see a drastic reduction in both physical and mental symptoms that are associated with it.

PD sufferers that seek out stem cell treatment experience replenishment on a cellular level.

This can lead to improvement in such things as:

Brain fog
Difficulties with Speech
Muscle spasms
Rigidity and Pain

Stem cells used to treat Parkinson's Disease target production of what is known as 'dopaminergic neurons' in order to combat dopamine deficiency. Stem cells with the ability to do so can be sourced from various different areas around the human body, and are either sourced from the patient themselves (as is the case with 'autologous' treatment) or from a donor (known as 'allogeneic' treatment).

These cells can be found in bone marrow, fat and in umbilical tissue. Treatment using umbilical tissue - referred to as embryonic stem cell treatment - is often favoured over treatment using adult stem cells due to a dramatic increase in potency.

About The Harley Street Skin Clinic

The award winning clinic dedicated to helping you be your best self

We understand that deciding to go forward with cosmetic treatment can feel like a huge decision. One that we certainly wouldn't expect you to go ahead with without hearing a little bit about us first. Here is exactly why people around the world are happy to put their trust into Harley Street Skin Clinic.

The Harley Street Skin Clinic
Quality & Safety is our Culture

Since 2004, Harley Street Skin has been on speed dial to some of the world's highest flyers thanks to the expertise of cosmetic tour de force, Dr. Aamer Khan and wife Lesley Reynolds.

With their flagship clinic based on the world’s most famous medical strip, Harley Street Skin quickly became a medical and cosmetic frontrunner, drumming up a pristine professional reputation and impressive roster of celebrity clientele. The clinic was in fact so thriving that it gained the attention of television network SkyOne, becoming the focus of hit documentary series Stitch Me, Lift Me, Tuck Me.

Offering an expansive range of both surgical and non-surgical treatments, Harley Street Skin are renowned worldwide for their cosmetic precision, expertise and minimally invasive techniques. From top of the line body sculpting treatments and cosmetic contouring to breast enhancement and discreet anti-ageing lifts, Harley Street experts offer the A-list experience from consultation through to aftercare.

But that's not all. Harley Street Skin are also pioneering skincare specialists, offering solutions to everything from anti-ageing and resurfacing, to colour correction and hydration.

Carefully formulating the perfect regime for even the most stubborn and unusual of skin complaints, Harley Street Skin boast an acclaimed skin care range frequently making an appearance in beauty mag must-haves, health and lifestyle columns, and celebrity handbags around the world.

With highly skilled practitioners, doctors and surgeons on hand at every turn, Harley Street Skin can help you attain the aesthetic you've been dreaming of - whatever your cosmetology needs.

Dr Aamer Khan & Lesley Khan