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Around 150,000 people have a stroke every year in the UK and most are ischemic, 'ischemic' meaning it involves the loss or obstruction of the blood supply to the brain. This means billions of brain cells die due to being deprived of oxygen and are no longer able to send signals elsewhere. Around half of people who survive a stroke are left with lasting disability as a result.
Injecting stem cells can fuel the repair process by them travelling to the site of brain trauma and replicating into any type of brain cell. Rapid stem cell treatment has been found to be effective, with the optimal time being between 36 and 72 hours after the stroke. Neural stem cells naturally repair small amounts of brain damage so stem cell technology could be a boon to stroke patients looking to repair at a faster rate.
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This cell-based regenerative medicine offers more than just the replacing of damaged cells within the brain.
Stem cells can also regulate the immune system to prevent any further damage to the body and brain, which is why it’s so important to administer treatment early post-stroke. Mesenchymal stem cells can be deployed in distant arteries before being carried to the parts of the brain needing repair.
Clinical trials carried out by the Stanford University School of Medicine found an average increase of 11.4 points on the Fugi-Meyer Assessment, an impairment test specifically for stroke sufferers, following stem cell treatments and all participants demonstrated improved motor function. Studies such as these have shown stem cell technology as a safe and effective form of treatment for long-term recovery in stroke patients.
The average patient loses 1.9 million neurons for every minute an ischemic stroke is left untreated, as well as 13.8 billion synapses and 7 miles of axonal fibers. Each hour without treatment is worth 3.6 years of ageing in terms of how many neurons the brain loses. Neural stem cells can help to repair the damage caused on a long-term basis.
Stroke triggers a strong inflammatory response in the moments following the incident - this activation of the immune response occurs in both ischemic and hemorrhagic stroke. Stem cell treatment for stroke works because it is able to change the nature of these chemical signals and combat the inflammation by regulating the immune system and any subsequent damage.
Studies show that the use of mesenchymal stem cells reduces necrosis in the brain tissue and improves overall motor function. By injecting stem cells, they move to the brain and multiply into lost brain cells caused by inadequate blood supply to the brain as a result of the stroke. Research further shows that this is an effective treatment for many months after the stroke.
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Every step of your journey with Harley Street Skin is handled with the utmost care and diligence. From your very first consultation, right the way through to follow up and aftercare, Harley Street Skin will guide, advise and support you at every given opportunity. We want to make sure that your time with us is as special to you, as you are to us...
The answer to some of the most common questions you may have
It's only natural to have questions if you are considering pursuing a treatment for the first time, and at Harley Street Skin, it's important to us that you feel confident and comfortable at every stage of your journey. To help you find the answers you need, here are a few of the more common quibbles that we find our clients frequently ask...
There are two main causes of strokes: either a blocked artery (an 'ischaemic stroke') or leaking/bursting of a blood vessel (a 'haemorrhagic stroke').
Some other may simply experience a temporary disruption of blood flow to the brain, which is referred to as a 'transient ischaemic attack', that does not cause any lasting symptoms.
The main cause of haemorrhagic stroke is high blood pressure, which can weaken the brain’s arteries and increase the likelihood that they will go on to split or rupture. Ischaemic strokes, on the other hand, happen when a blood clot forms and blocks the flow of blood and oxygen to the brain. These usually form in areas where the arteries have narrowed or become blocked over time in a process known as atherosclerosis.
Clinical trials using stem cells have shown that, combined with clot busting and thrombectomy, recovery can be significantly sped up.
Stem cells injected directly to the affected area, or into arteries elsewhere in the body, travel to the brain to fuel and accelerate the necessary repair process.
It works as the stem cells differentiate into different brain cell types and thus replace the damaged tissue and lost cells during and after the stroke incident itself.
Stem cells also work to regulate many inflammatory and immune responses which can cause lesions on the brain, thus reducing the size of these lesions and helping to prevent cell death at the same time.
Internal repair begins straight away with stem cells best injected between 36 and 72 hours after the stroke incident has taken place.
The effects of treatment are long-term as continual treatment brings about regenerative benefits which can remain with the patient indefinitely.
Trials have shown significant improvements in arm and leg function over a 12 month period after the stem cell transplant. This is promising as research tells us there is a real need to reduce the neurological deficit caused by a stroke in the subsequent years.
Stem cells can be harvested from adipose cells (fat), bone marrow, or umbilical lining (embryonic stem cells).
Some people prefer to use their own adult stem cells for treatment, while others will opt for embryonic stem cells due to their significantly higher potential for regrowth and repair.
Embryonic stem cells are harvested soon after birth in a regulated lab and are always screened for infection, genetic abnormality and disease.
Otherwise neural stem cells can be sourced from an adult donor, as these also have the ability to differentiate into three major central nervous system cell types: neurons, astrocytes and oligodendrocytes.
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We understand that deciding to go forward with cosmetic treatment can feel like a huge decision. One that we certainly wouldn't expect you to go ahead with without hearing a little bit about us first. Here is exactly why people around the world are happy to put their trust into Harley Street Skin Clinic.
Since 2004, Harley Street Skin has been on speed dial to some of the world's highest flyers thanks to the expertise of cosmetic tour de force, Dr. Aamer Khan and wife Lesley Reynolds.
With their flagship clinic based on the world’s most famous medical strip, Harley Street Skin quickly became a medical and cosmetic frontrunner, drumming up a pristine professional reputation and impressive roster of celebrity clientele. The clinic was in fact so thriving that it gained the attention of television network SkyOne, becoming the focus of hit documentary series Stitch Me, Lift Me, Tuck Me.
Offering an expansive range of both surgical and non-surgical treatments, Harley Street Skin are renowned worldwide for their cosmetic precision, expertise and minimally invasive techniques. From top of the line body sculpting treatments and cosmetic contouring to breast enhancement and discreet anti-ageing lifts, Harley Street experts offer the A-list experience from consultation through to aftercare.
But that's not all. Harley Street Skin are also pioneering skincare specialists, offering solutions to everything from anti-ageing and resurfacing, to colour correction and hydration.
Carefully formulating the perfect regime for even the most stubborn and unusual of skin complaints, Harley Street Skin boast an acclaimed skin care range frequently making an appearance in beauty mag must-haves, health and lifestyle columns, and celebrity handbags around the world.
With highly skilled practitioners, doctors and surgeons on hand at every turn, Harley Street Skin can help you attain the aesthetic you've been dreaming of - whatever your cosmetology needs.