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Body Concerns
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Skin Concerns
Discreet, expert treatments for the body and intimate areas, delivered in complete privacy.
Body Contouring
Reshaping and firming treatments that refine your silhouette and smooth stubborn areas.
Intimate Treatments
Sensitive, confidential care for intimate areas, carried out by experienced practitioners.
Restorative hair treatments and finishing touches that frame and complete your look.
Hair Loss
Evidence-based treatments to restore density and the appearance of a fuller hairline.
Lashes & Permanent Makeup
Long-lasting enhancements that define your features and simplify your daily routine.
Expertly administered injectable treatments to smooth lines, restore volume and refresh tired skin.
Botox
Precise botox that soften expression lines and refine facial balance.
Fillers
Tailored filler treatments that replace lost volume and sculpt your natural contours.
Skin Boosters
Deep hydration and cellular repair delivered directly into the skin for a lasting glow.
Advanced device-led treatments that resurface, tighten and even out the skin without surgery.
Laser & IPL
Targeted laser and light energy to treat pigmentation, redness and uneven texture.
Skin Tightening & Lifting
Non-surgical lifting and firming for a more defined jawline, cheeks and neck.
Expert care for a wide range of skin conditions, ensuring healthy, radiant skin.
Chemical Peels
Controlled resurfacing peels that lift pigmentation, refine texture and reveal fresher skin.
Facials & Cleansing
Rejuvenating facial treatments to cleanse, resurface and enhance your natural radiance.
Microneedling
Collagen-boosting treatments that soften scarring, refine pores and firm the skin.
Veins & Blemishes
Comprehensive care for skin lesions and bumps, promoting clear and healthy skin.
Comprehensive solutions to address a range of body concerns, from stubborn fat to skin laxity.
Shape & Contour
Specialised treatments to refine stubborn pockets of fat, dimpling and contour irregularities for a balanced silhouette.
Skin Laxity & Marks
Firming and resurfacing treatments for loose body skin, stretch marks and post-pregnancy skin changes.
Veins & Thread Veins
Effective clearance of visible leg veins and thread veins to restore an even, unblemished appearance.
Expert treatment for the concerns that show first — lines, lost volume, tired eyes and slackening skin across the face, jawline and neck.
Eye Area
Focused treatment for the delicate eye area, where puffiness, hollowing, hooding and fine lines make you look tired.
Lines & Wrinkles
Smoothing treatments for the expression and static lines that form across the forehead, mouth and neck over time.
Sagging & Laxity
Lifting and tightening solutions for jowls, softening cheeks and a loss of definition through the jawline and neck.
Volume & Contouring
Tailored solutions to restore facial volume and enhance natural contours for a more youthful appearance.
Restorative and enhancing treatments for thinning hair, sparse brows and lashes that lack lift.
Brows & Lashes
Enhancement for sparse brows and straight, downturned lashes to frame and open up the eyes.
Hair Loss
Diagnostic-led treatment for thinning, shedding and patchy hair loss, including postpartum and autoimmune causes.
Targeted care for the health and appearance of your skin, from acne and rosacea to pigmentation, texture and scarring.
Acne & Blemishes
Clinical management of active breakouts, congestion, enlarged pores and the scarring acne leaves behind.
Pigmentation & Skin Tone
Corrective treatments for dark patches, sun damage and an uneven complexion, for clearer and more even skin.
Scars, Marks & Skin Lesions
Treatment and removal options for scars, burns, raised lesions and sun-related skin growths.
Sensitive & Inflamed Skin
Calming, evidence-based care for reactive, red and inflamed skin, including rosacea and eczema.
Texture & Skin Quality
Resurfacing and hydrating treatments for rough, dry or lacklustre skin that has lost its smoothness and glow.
When a friend uses your referral code, they'll get £50 off their first treatment, and you'll get £50 off your next one.
The more friends you invite, the more you earn.
★★★★★
20 Years of Safety: Trust in our 20 year track record and history of excellence
Award Winning Clinic: Over the last two decades we've received multiple awards
We do aesthetics better
While we are a skin clinic based in London, our impact is much greater. We focus on bringing excellent skin care to patients around the world.
Our experienced doctors are experts in cutting-edge dermatological procedures and skincare. You’re in luck when you choose us for skincare, because our team is here to meet all of your skincare demands.
Experience remarkable results with Polynucleotides. These treatments effectively diminish fine lines and wrinkles, leaving your complexion visibly smoother and more even.
Understanding Polynucleotides: The Key to Skin Regeneration
Polynucleotides, abbreviated as PN, is an innovative treatment from DNA traces turned into the most powerful dermatology procedure to have ever existed. This treatment stimulates collagen and elastin production and healing of post-inflammatory hyperpigmentation (redness) due to acne or sun damage. It also moisturizes your skin so that it looks plumper and radiant. Plus, these molecules reduce inflammation, irritation, redness, increase skin elasticity, and make you look younger. Giving your skin a dose of PN makes your skin look fresh and renewed.
Several effects of a Polynucleotide:
30 minutes - 1 hour
Not Required
None
Immediately
Immediately
Varies
24 Hours
24 Hours
Polynucleotides take a regenerative approach to skin health. They are naturally derived and support your cells by repairing and hydrating tissue. What I find particularly valuable is how they enhance the skin’s ability to restore itself over time. Unlike treatments that simply mask the signs of ageing, polynucleotides work to address the causes.
Dr Aamer Khan
MSC, CHD, MSBC
GMC: 3128431
It is preferable to begin with a consultation in which expectations regarding the procedure, necessary preparations, and actions to be taken prior to, during, and following the surgery are established.
We are now focused on all the preparations that must be taken. Making sure everything will go along to plan financially, emotionally, and physically before the procedure begins.
Polynucleotide treatments are excellent in promoting tissue healing, increasing collagen, and elastin production. Consequently, it leads to well-hydrated firmer skin that has reduced fine lines and wrinkles as well as a better surface texture. Polynucleotide is more than just filler.
The recovery time for polynucleotide injections is usually 1–2 days. However, recovery time can vary depending on the method used to administer the injections.
It is preferable to begin with a consultation in which expectations regarding the procedure, necessary preparations, and actions to be taken prior to, during, and following the surgery are established.
We are now focused on all the preparations that must be taken. Making sure everything will go along to plan financially, emotionally, and physically before the procedure begins.
Polynucleotide treatments are excellent in promoting tissue healing, increasing collagen, and elastin production. Consequently, it leads to well-hydrated firmer skin that has reduced fine lines and wrinkles as well as a better surface texture. Polynucleotide is more than just filler.
The recovery time for polynucleotide injections is usually 1–2 days. However, recovery time can vary depending on the method used to administer the injections.
Alyssa Rya
Had Dr Omar for masseter Botox for the first time. He was very knowledgable and king and made sure I was completely at ease before injecting. Couldn’t recommend enough! Thanks again!
14th September 2026
MARK BARANDINO
I had my consultation with Dr Khan, I was conflicted as to what treatment I needed for my condition and he was patient, talked me through my options and took the time to listen to my concerns. I would highly recommend payibg a visit to the clinic, even for an initial consultation.
15th September 2026
Ayo
What an amazing clinic, Elizabeth was very welcoming and warm when I first arrived and Rose is extremely knowledgeable and was very helpful in tailoring a treatment programme that suited my specific needs. Would highly recommend!
12th September 2026
Roy
Dr. Omar is incredible!!! He provided amazing advice that was clear, concise and realistic and explained new advanced treatments that will yielded incredible results and I can’t wait to get started!!
11th September 2026
Ibrahim Kitabu
The reception are well welcoming, they offered me drinks and the doctor was great in his explanation in every part of the examination. Great experience will definitely recommend.
4th September 2026
Polynucleotide treatments are possible through the use of either needles or tubes that are based on individual needs. Fine lines and wrinkles are targeted more precisely by needles compared to cannulas, which are good for larger areas and promote less bruising. A numbing cream should be expected to help soothe any stinging feeling. The procedure typically takes 15-30 minutes. Immediately after mild side effects like swelling or redness may follow. In order to heal totally, you need a treatment plan for sessions two or three weeks before big events. Minimizing downtime while enhancing the deep skin renewal is the ultimate goal here.
You may anticipate significant changes in aging symptoms such as wrinkles and fine lines after the treatment, also, it helps skin firmness leading to smoother skin texture. This treatment also results in an even skin tone, seeming and feeling moisturized while being velvety soft. With regular sessions, there is a marked transformation that rejuvenates the skin making it look youthful again.
Peptides act like healers and they help in aiding the skin tissues leading to the disappearance of acne scars over time. Use them more frequently and those marks will become less visible and your skin will look smoother and more even. The polynucleotide treatment also induces collagen that repairs sun damage and improves texture. Your face can look more attractive because of the skin health, these fixes can eliminate dark spots, wrinkles, etc.
Polynucleotides rescue sun damaged skin. It increases collagen production and rejuvenates the skin that results in gradual reduction of sunspots, finer lines on the face, and discolored pigmentation over time. With continued maintenance of polynucleotide treatment, it will bring back your youthful glow. Always make sure you don’t miss any of your treatments so that you get optimal outcomes.
Some clients might experience instant improvement such as increased moisture levels or a glowing effect. However, having smooth skin and reducing wrinkles is something that takes time. You will notice the full effects of the polynucleotide treatment after some sessions when your skin regeneration starts from within. Frequency of treatments will depend on your skin type and what you want to achieve with your skin. In most cases, one receives several treatments over several weeks or months to achieve desired outcomes. In most cases, you will need between three to six sessions depending on how much work your skin requires.
Polynucleotides possess versatility in treating different body parts. They can improve a person’s appearance within weeks from facial moisturizers that are also suitable for the neck and hands to those which rejuvenate any part of the body. Although facial rejuvenation is one common use for polynucleotides, they can also work wonders elsewhere on the body as well. It could even include sagging arms, legs, and thighs. In some instances, stretch marks and cellulite may appear less pronounced while skin might feel smoother and more toned after several sessions. That’s how you can rejuvenate your whole body through a Polynucleotide session.
With polynucleotide treatment involving injections, you may feel a tiny pinch or sting from the needle. This mild discomfort usually goes away quickly although certain parts of the body may experience more pain than others. Moreover, if you fear any form of pain before the procedure, you should consider using numbing cream on your skin to ensure no pain during the process. Applying polynucleotides topically is pretty straightforward. Creams or gels used for this purpose are mild so they do not cause any pain or discomfort as they are applied on the skin surface. Even better, some people find this activity to be relaxing. However, everyone’s skin is unique, individuals who experience itching or tenderness are always encouraged to report to medical practitioners involved, then treatment will continue as planned.
Amie-mara M.
Very good advice and amazing staff!
11th September 2026
TROY The MAGICIAN
Amazing service as always!
10th September 2026
N El
Easy in and out and explained everything for me :)
10th September 2026
Siobhan Shaw
Responsive and helpful
9th September 2026
Felix Gabriel Mance
Very good consultation with dr Tee
9th September 2026
Emma Shakeshaft
Great experience at Harley Street Skin.
7th September 2026
Hazael Wihanto
Really quick and straightforward
7th September 2026
Camilla Alge
Super frieny
7th September 2026
Lorena Fernandez
Amazing! Skin looks radiant after water peel.
24th August 2026
A Zul
Dr Tee was excellent with me thanks you ✨
19th August 2026
Polynucleotide at Harley Street Skin Clinic administer this treatment with skill and expertise. Employing safe, long-established procedures and high-quality medical materials.
This is how how much our Polynucleotide costs:
Doctor:
Senior Doctor:
Lead Doctor:
Our prices represent the expertise of our GMC-registered doctors, the superior quality of the products we use and the convenience and comfort of our clinic. Elsewhere in the UK, in places such as Manchester, Newcastle or Leicester, the cost of treatments is less expensive, and treatments start from £250 per session upwards. But, there can also be less quality methods or end results with them. By choosing Harley Street SKin Clinic, you are choosing reputable care from individuals who care first and foremost about your safety and satisfaction.
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Stop your routine skin care for about one week before having your polynucleotide treatment. By suspending the use of topical products on your skin. This is a general rule; however, it is prudent to consult experts who can give advice that specifically caters to your skin’s necessities.
After the treatment of polynucleotides, one is recommended to avoid anything that might irritate your skin. These may include extreme sunlight exposure, excessive sweating during intense workouts as well as heavy cosmetics. Having gentle routines for skin care and taking note of what our skins need is a good way to ensure a smooth and successful recovery.
No specific dietary or lifestyle changes are needed, simply have a healthy living style which will help in prolonging the advantages that can be derived from polynucleotide treatment. This involves eating a balanced diet with lots of nutrients and minerals, ensuring that dehydration does not occur, limiting sun exposure, as well as using mild skincare products. It’s also important to know that skin treatments last longer if you are in good health generally.
Get that bounce back in your skin, as it becomes tighter and more elastic.
Say goodbye to sagging skin with a natural facelift.
Skin that is strong enough to fight off aging.
Most activities can be resumed right after polynucleotide treatments. However, you should avoid heat exposure such as hot baths/showers and steam rooms for 48 hours after treatment. You may also want to wait 24 hours before resuming exercise routines. Your practitioner will give you complete instructions on what to do afterwards.
After getting polynucleotide treatment, people usually experience a 3-5 days swelling period before the body completely digests it. Avoid sun exposure and use mild cleansers.
While full results are usually seen around 5 weeks after the final session, many clients notice gradual improvements leading up to this point.
Polynucleotide injections are generally safe, but it’s necessary to consult with a qualified medical practitioner to assess the suitability. Pregnancy, breastfeeding, active skin infections, autoimmune disorders, bleeding disorders and allergies are examples of factors that may make individuals unsuitable for this treatment. Polynucleotides are made from fish and therefore they cannot be used by vegans. Although most people can tolerate its administration without problems because it suits any kind of skin including sensitive skins.
Polynucleotides usually have good tolerance, and the only adverse effects are injection site reactions like redness, swelling and bruising. The latter is not common. It is important to have proper consultation prior to treatment so that all possible risks can be evaluated for a particular patient. Such patients should be careful if they are allergic to seafood because despite the purification process which helps in reducing chances of DNA allergic reactions, they may still suffer from such conditions. Polynucleotide injections must not be given to pregnant or nursing women, as well as those planning to become pregnant soon.
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We're based in central London at the historic 14 Devonshire Pl which is only a short 2 minute walk from Regents Park tube station a 10 minute taxi journey to Kings Cross, and St Pancras stations.
We're open Monday - Friday 8am - 8pm, and Saturdays 9am - 5pm, feel free to drop in to talk to a member of our team where they can answer any of your questions.
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