Introduction
Knowing the right Wegovy dose for weight loss is important if you want safe, steady, and long lasting results. Wegovy is an injection prescribed for weight loss that contains semaglutide, a medicine that helps you reduce appetite and improve feelings of fullness. But, it must be taken in a slow dosing schedule to allow your body to adjust and minimise side effects.
This guide explains everything you need to know about how Wegovy dosing works in the UK, what results you can expect, and how to optimise your treatment with lifestyle changes.
Quick Summary
- Starting dose is 0.25 mg once weekly
- Dose increase is every 4 weeks (0.5mg – 1 mg – 107 mg – 2.4 mg)
- Full maintenance dose is at 2.4 mg weekly by week 17
- There is a potential loss of around 15% of body weight in 12 months
- Combine Wegovy with a healthy diet and exercise
- Follow NICE/NHS guidance and avoid unregulated suppliers
Understanding Wegovy
What is Wegovy?
Wegovy was originally developed for type 2 diabetes. It is a branded form of semaglutide, which belongs to a group of drugs called GLP-1 receptor agonists. Later, it was found to support a significant weight loss at higher doses.
Wegovy is approved in the UK for adults with obesity with weight-related health conditions. It is injected once a week using a pre-filled pen that is designed for easy home use.
Related read: Wegovy London
cHow Wegovy helps you eat less
Wegovy copies a hormone your body already makes called GLP-1. This hormone helps manage hunger and digestion.
Wegovy helps in 3 ways:
- You feel less hungry
- You feel full longer
- Your blood sugar is manageable
Over time, these effects make it easier to eat smaller portions and stick to healthier habits.
The Right Wegovy Dose for Your Body
The usual long-term dose of Wegovy for weight loss is 2.4 mg once a week. This is called the maintenance dose and is the amount most medical studies use when measuring results.
Some people lose weight on lower doses and do not need to reach the highest dose because their appetite reduce quickly, their body is more sensitive to medication, and lower increases feel more comfortable
For these people, staying at a lower dose can still support consistent weight loss without unnecessary side effects. 2.4 mg is the standard target dose, but the best dose is the one that helps you lose weight safely and sustainably.
Doctors will consider the following:
- Your tolerance to the side effects
- Your weight loss rate
- Your overall health
- Other medicines you are taking
This is why strict medical supervision is important because of its personalised approach.
Recommended dosing (titration) schedule
Slow increase helps reduce side effects like nausea and stomach upset.
| Timeline | Dose | Frequency |
| Weeks 1 to 4 | 0.25 mg | Once a week |
| Weeks 5 to 8 | 0.5 mg | Once a week |
| Weeks 9 to 12 | 1 mg | Once a week |
| Weeks 13 to 16 | 1.7 mg | Once a week |
| Week 17+ | 2.4 mg | Once a week (maintenance dose) |
Wegovy Weight Loss Results
Weight loss does not happen overnight. Most patients notice:
- Their appetite reduced within the first 1 to 2 weeks
- There are early weight changes in the first month
- There are more visible results after 3 months
- There is steady progress over 6 to 12 months
Effective & professional doctor-led Wegovy at our central London clinic
Verified Before & After
Verified Before & After
Expected outcomes
Research shows that patients using the full dose of Wegovy lost around 15% of their body weight over 12 months on average.
Factors influencing results
There are several factors that affect how well Wegovy works:
- High protein diet, balanced meals leads to better results
- Regular exercise helps preserve muscle and boost fat loss
- Some people naturally have faster metabolism
- Missing doses can reduce effectiveness
Related read: How Quickly Does Wegovy Work? – UK Guide
Adjusting Your Wegovy Dose
When to consider adjusting your dose
Your doctor may need to review your dose if:
- Weight loss stalls for several months
- Side effects become unmanageable
- Appetite suppression feels too strong or too weak
How to safely increase or decrease dosage
If side effects occurs, doctors may recommend you to:
- Stay on the same dose for longer
- Reduce to the previous dose
- Slowing the titration schedule
Never jump doses or stop suddenly without the advice of your doctor.
What to do if side effects persist
There are common side effects of Wegovy which include nausea, bloating, and constipation, especially during dose increases. These usually improve with time.
These are the simple tips to reduce side effects:
- Eat smaller meals instead of large portions
- Avoiding oily or greasy foods
- Drinking enough water throughout the day
- Taking your injection on the same day each week
Related read: Why You Need to Increase Your Wegovy Dose & How It Works
Lifestyle Habits That Improve Results
Wegovy works best when you support it with daily habits:
- Including lean protein to your diet
- Eating more vegetables and high-fibre foods
- Avoiding sugary and processed foods
- Doing light exercises
These things help your weight loss feel more natural and easier to maintain.
Maintaining weight after Wegovy
Some people regain weight if they stop the treatment without changing their lifestyle. Long-term success depends on:
- Eating meals at regular times
- Staying physically active
- Monitoring weight changes
- Getting advice and support from a clinician
Related read: How Long Does Wegovy Stay in Your System?
Who Can Get Wegovy in the UK?
You can get Wegovy under medical guidelines set by NICE. It is offered to adults who meet the following conditions:
- BMI is 35 or higher
- BMI is 30 or higher with other health problems linked to weight
Many people choose to get Wegovy from private clinics, because getting it from private care means shorter waiting times, regular monitoring, and extra support in your healthy eating habits and lifestyle changes.
It is also important to get Wegovy from registered UK pharmacies and clinics. Buying it from unknown sellers is risky as these products may be fake, and unsafe.
Related read: How to Inject Wegovy: Expert Tips for UK Users
FAQs
- What is the starting dose of Wegovy for weight loss?
You start with 0.25 mg once a week for the first four weeks. Your body needs first to adjust to reduce the side effects.
- How long does it take to reach the highest dose of 2.4 mg?
It usually takes about 16 weeks to each the full 2.4 mg.
- Can I stay on Wegovy longer than 1 year?
Yes. Consistency is important to reach your goal. But long-term use should always be monitored by a clinician.
- What weight loss results can I expect?
Average results are at 15% loss in body weight when using the full dose with lifestyle changes.
- What side effects can I expect during titration?
Common side effects to look out for are nausea, vomiting, bloating, constipation, and tiredness.
- Can I access Wegovy on the NHS in the UK?
Yes. But it is limited and usually part of specialist obesity services. Many patients choose private clinics for faster access.
Reserve a Wegovy appointment
One of our experts will be more than happy to answer any questions you have.
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Excellent service as usual
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Dr Basu was kind & helpful - we were able to do the procedure on the day which was great!
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