Introduction
PRP microneedling is a skin rejuvenation treatment that combines microneedling with platelet-rich plasma (PRP) that is taken from your own blood. This treatment boosts faster skin healing, increases collagen production, and results in more visible skin improvements.
What is PRP Microneedling?
Microneedling is a minimally invasive procedure that uses tiny needles to create micro-injuries in your skin to trigger your body’s natural healing response.
How does it work?
Microneedling works by stimulating the production of collagen and elastin and elastin after your skin notices the tiny punctures. Collagen provides structure, while elastin gives the skin its elasticity, and over time, this process smooths texture, reduces scarring, shrinks pores and softens fine lines.
Standard microneedling alone works very well. But when you add PRP, you are giving your skin an extra healing boost.
What is PRP and how it is used in aesthetic medicine
PRP stands for platelet-rich plasma. It is made from your own blood and contains high amounts of platelets and growth factors that help the body heal and repair itself.
In aesthetic medicine, PRP is used to improve the quality of the skin, support healing, and boost collagen. It is often used for treatments like microneedling to help reduce fine lines, acne scars, and uneven texture.
Making PRP is a simple process:
- A small sample of blood is taken from your arm, similar to a routine blood test.
- The blood is placed in a machine called a centrifuge, which spins it to separate its different parts.
- The PRP is then collected.
- The PRP is applied to your skin during the microneedling treatment.
PRP is safe to use because it comes from your own blood which means it carries a very low risk of allergic reactions.
Related read: Microneedling London
Why Combine PRP with Microneedling?
Microneedling creates tiny channels in the skin. These allow PRP to go deeper into the skin where it can work more effectively. When used together, they support better healing and usually give stronger results than microneedling alone.
Sign 1: Your Skin Feels Smoother and Looks More Even
Uneven skin texture can be caused by acne scars, sun damage, ageing, or everyday wear and tear. PRP microneedling helps improve this by encouraging your skin to renew and repair itself.
The treatment can:
- Boost collagen production to make the skin smoother.
- Replace old and damaged cells with healthy ones.
- Evening out the skin colour by the help of growth factors that control melanin and reduce dark spots.
- Refining surface by encouraging skin to reorganize evenly.
Sign 2: Fine Lines and Wrinkles Look Softer
Collagen starts to slow its production as you age. By the age of 30, you have lost about 30% of your skin’s collagen and this continues through your 40s and 50s.
PRP microneedling helps by boosting your collagen production. PRP’s growth factors signal your skin’s collagen production to work harder.
PRP microneedling works best for early signs of ageing, If you are in your 30s or early 40s and start to notice changes, this treatment can help prevent them from worsening. But for deeper wrinkles, you may be recommended to combine it with other treatments to achieve better results.
Sign 3: Acne Scars Look Fainter and Pores Appear Smaller
One of the benefits of PRP microneedling is improving acne scars and large pores. Atrophic acne scars (the depressed, pitted scars after acne heals) cannot be treated by a standard treatment. They create uneven surfaces that makeup cannot hide.
Why it works very well for acne scars:
- Collagen filling: new collagen builds under depressed scars and lifting them up
- Tissue regeneration: PRP’s growth factors actively repair damaged tissue
- Faster healing: the combo speeds up skin’s natural repair
- Multiple sessions build results: three sessions spaced once month apart work best
Pore size reduction:
Another skin concern that PRP microneedling targets is large pores. When collagen improves around pore openings, pores look smaller. This treatment tightens the skin and naturally reduces pore size.
Sign 4: Enhanced Skin Glow and Radiance
What creates the glow:
- More cell turnover by replacing old cells by fresh young ones.
- Boost blood circulation by bringing oxygen and nutrients.
- Improve skin texture that results in natural brightness.
- Less pigmentation means your skin is more even colour.
Before and after expectations:
The transformation is not instant. You will notice the initial improvement at around 2 to 4 weeks as collagen begins to produce, and final results show after 8 to 12 weeks when collagen in your body fully rebuilds.
Sign 5: Shorter Downtime and Faster Recovery
Growth factors found in PRP actively accelerate healing. Research confirms this in a 2019 review that adding PRP to microneedling lessens downtime after the procedure
Related read: Discover How Long Microneedling Effects Last | Glow Insights
Sign 6: Clinically Measurable Collagen and Elastin Boost
The most convincing sign PRP microneedling works is hard scientific evidence.
What research show:
- Split-face study (50 acne scar patients)
- PRP microneedling side shows 62.20% improvement
- Microneedling alone shows 45.84% improvement
- Meta-analysis (8 studies, 311 participants)
- Significant scar severity reduction with PRP
- Combination therapy significantly better than alone
- 2016 study (20 women with ageing skin)
- PRP alone did not show dramatic results for women over 45
- Younger patients with less-severe wrinkles responded better
- Suggests PRP microneedling works best for early ageing prevention
Effective & professional 7 Signs That Prove PRP Microneedling Works -led Botox at our central London clinic
Sign 7: Long-Term Maintenance with Fewer Repeat Treatments
Once you invest in PRP microneedling, you would not need to keep coming back as frequently as with other treatments.
Typical treatment plan:
- Initial course: 3 to 4 sessions spaced 4 to 6 weeks apart
- Maintenance: every 6 to 12 months depending on goals
Collagen and elastin do not quickly disappear. They act like support for your skin and help keep it firm and strong. Because of this, many people continue to see improvements for around 6 to 12 months after their first treatment session.
Related read: When to Wash Face After Microneedling with PRP
Is PRP Microneedling Right for You?
You are a good candidate if you:
- Are younger patients (30s to early 50s) with early signs of ageing.
- Have acne scars, fine lines, uneven texture, large pores, dullness, early wrinkles.
- Wants minimal downtime, natural-looking results, and longer-lasting effects.
- Can invest £395 to £550 per session.
Contraindications and What to Avoid
You should not get PRP microneedling if:
- Pregnant or breastfeeding
- Active acne or skin infection on your face
- Using isotretinoin (Accutane), wait 6 months after stopping
- Have eczema, psoriasis, or rosacea in treatment area
- Have platelet or blood disorder
- Had major surgery within the last 6 months
- Have HIV, chronic illness, or uncontrolled diabetes
- History of keloid scarring or bruise easily
- Have herpes simplex (cold sores) on the face
What to avoid before the treatment:
- Stop retinol/tretinoin 5 to 7 days before
- Avoid heavy sun exposure 2 weeks before, use sunscreen daily
- Wait 24 hours post-treatment before applying makeup
Related read: Can I Use Niacinamide After Microneedling: Post-Care Essentials
What to Expect: Session, Recovery and Cost
Each session takes about 60 to 90 minutes, this include:
- Blood draw: getting small sample from the arm
- Centrifuge: blood is spun in the centrifuge to separate PRP
- Cleansing: the face is thoroughly cleaned
- Microneedling: the device glides over the skin
- PRP application: PRP is applied using a gauze soak
- Rescue gel: healing product is applied
Related read: 5 Things You Should Know To Identify How Long Your Microneedling Session Takes
What you will feel
- Pain or discomfort during treatment
- Burning or stinging
Most clinics apply numbing cream to minimise discomfort
After your session
Typical recovery timeline:
| Timeline | What to Expect |
| 24 to 48 hours | Redness, warmth, and light swelling |
| 3 to 5 days | Flaking or peeling as the skin heals |
| 1 week | Full recovery |
UK Pricing
Cost depends on many factors, which includes:
- Area treated
- Device used
- Whether PRP is included
- Clinic reputation and practitioner qualifications
The basic cost ranges from £395 to £550 per session. But with maintenance only every 6 to 12 months, this becomes cost-effective compared to monthly treatments.
Always ask for a full breakdown during consultation.
Risks, Side Effects and How to Minimise Them
PRP microneedling is considered safe when performed by experienced clinicians. But it is not risk-free.
Common side effects include:
- Redness
- Swelling
- Bruising
- Flaking/peeling
- Burning/stinging
Less common risks are:
- Infection
- Pigmentation changes
- Acne flare
- Milia
- Cold sore flare
How to minimise risks
- Choose a qualified practitioner: GMC registered doctor or board-certified dermatologists
- Very sterile equipment: medical-grade single use needles
- Follow aftercare: do not skip aftercare to prevent complications
- Avoid sun: use sunscreen daily and avoid excessive sun exposure for 2 weeks post treatment
- Do not use retinoids immediately: wait until skin heals
- Monitor for severe symptoms: contact clinician for severe pain, unusual swelling, and infection signs
Related read: 7 Best Moisturisers to Use After Microneedling
How to Choose a Premium Clinic for PRP Microneedling
In the UK, you want a premium clinic for your PRP microneedling.
Here is what to check:
| Factor | What To Look For |
| Practitioner qualifications | GMC-registered doctor, board-certified dermatologist |
| Experience | Ask how many PRP microneedling treatments they have done |
| Device type | Medical-grade FDA-approved device |
| Needle depth | Customised to your skin type |
| Before and after photos | Real patient evidence |
| Hygiene | Clean clinic, sterile needles, proper blood draw |
| Consultation | Thorough assessment, not sales-focused |
| Aftercare | Clear instructions, follow-ups, accessible questions |
FAQs
- When will you see results from PRP microneedling?
You may see early changes after 2 to 4 weeks, as your skin begins producing more collagen. Full results appear after about 8 to 12 weeks.
- How many treatments do you need?
Most clinics recommend 3 to 4 sessions spaced 4 to 6 weeks apart. After that, maintenance sessions are done every 6 to 12 months.
- What to expect during recovery?
You may experience mild redness, warmth, swelling, flaking, and full recovery in about a week.
- Is PRP microneedling safe?
Yes. It is generally safe especially when done by a professional.
- How much does it cost in the UK?
In the UK, PRP microneedling usually costs around £300 to £550 per session, depending on clinic location, device used, and if PRP is included.
- Can PRP microneedling be combined with other treatments?
Yes. It can be combined with lasers, peels, and skin care to achieve your goals.
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One of our experts will be more than happy to answer any questions you have.
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